Mirjana Medenica, PhD

Dr sc. Mirjana Medenica

Position: Professor
Organizational unit: Department of Physical Chemistry and Instrumental Methods
Address: Vojvode Stepe 450, 11221 Belgrade, Serbia
Room:  B004
Phone: +381 11 3951-291
Fax: +381 11 3972-840
Email: medenica@pharmacy.bg.ac.rs


Mirjana Medenica was born on July 20th 1952 in Ptuj, Slovenia. She finished primary and secondary school in Belgrade. She graduated in 1976 at the Faculty of Pharmacy, University of Belgrade. She has been employed at the Faculty of Pharmacy since 1976. She was awarded a Master of Science title (MSc) in 1982 and defended her PhD dissertation in 1988 at the Faculty of Pharmacy, University of Belgrade. She was promoted to assistant professor in 1991, associate professor in 1996 and professor of Physical Chemistry in 2001.

Mirjana Medenica is a Head of Department of Physical Chemistry and Instrumental Methods at the Faculty of Pharmacy, University of Belgrade (since 2007). She teaches Physical Chemistry and Instrumental methods at the undergraduate level; Physical-chemical phenomena and instrumental methods and Spectroscopic methods in drug analysis at doctoral studies, as well as Selected instrumental methods at advanced specialist studies required by the healthcare system of several modules at the Faculty of Pharmacy in Belgrade.

She wrote a textbook titled Experimental Physical Chemistry, (two editions in 1998 and 2002) and Experimental Physical Chemistry and Instrumental Methods (two editions in 1994 and 1996). She was an editor of the capital monograph 60 years of the Faculty of Pharmacy in Belgrade, from 1945 to 2005, published in 2006.

Mirjana Medenica is a Leader of the Scientific Project: Modelling different chromatographic systems with chemometric approach in pharmaceutical analysis (172052 for period 2011–2016), funded by the Ministry of Education, Science and Technological Development of Republic of Serbia. She was a Leader of several scientific projects from 1991 up to now. She published 230 scientific papers, of which 116 printed in international (90) and national journals (26), all with recensions, and 114 papers presented at international scientific conferences. She was mentor of 3 defended doctoral dissertations and 3 defended master thesis, as well member of numerous committees for the defense of doctoral dissertations, master thesis and specialist works. She was a reviewer for 5 university textbooks and reviewer for scientific projects and papers in the numerous international scientific journals.

Research interest: Study of physico-chemical propeties of medicines and develop of modern methods of analysis. Formulation and characterization of separation systems for modelling retention behaviour of medicinal substances by chemometric evaluation. Study of diferent chromatographic systems with MS detection.

Mirjana Medenica was a member of several University boards and numerous Commission at the Faculty of Pharmacy in Belgrade.

She is the winner of the Plaque, the highest recognition of the Pharmaceutical Society of Serbia, for significant results in improving the pharmaceutical profession and science (2008).

  • Jovanović, M., Rakić, T.,Jančić–Stojanović, B., Ivanović, D., Medenica, M.: Retention mechanisms assessment and method development for the analysis of iohexol and its related compounds in hydrophilic interaction liquid chromatography. Anal. Bioanal. Chem. 2014, 406: 4217–4232.

  • Vemić, A., Malenović, A., Medenica, M.: The influence of inorganic salts with chaotropic properties on the chromatographic behavior of ropinirole and its two impurities, Talanta 2014, 123: 122–127.

  • Kostić, N., Dotsikas, Y., Malenović, A., Medenica, M.: Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs, Talanta 2013, 116: 91−99.

  • Rakić, T., Jančić–Stojanović, B., Malenović, A., Ivanović, D., Medenica, M.: Demasking large dummy effects approach in revealing important interactions in Plackett–Burman experimental design. J. Chemometrics, 2012, 26: 518–525.

  • Jovanović, M., Rakić, T., Jančić–Stojanović, B., Malenović, A., Ivanović, D., Medenica, M.: Assessment of β-lactams’ retention in hidrophylic interaction chromatography applying Box–Behnken design. J. Sep. Sci., 2012, 35: 1424–1431.

  • Jančić–Stojanović, B., Rakić, T., Kostić, N., Vemić, A., Malenović, A., Ivanović, D., Medenica, M.: Advancement in optimization tactic achieved by newely developed chromatographic responce function: Application to LC separation of raloxifene and its impurities. Talanta 2011, 85(3): 1453–1460.

  • Medenica, M., Ivanović, D., Popović, I., Malenović, A., Jančić, B.: Computer–Assisted Optimization and Validation of LC Analysis of Trimetazidine Dihydrochloride and its Impurities. J. Chromatogr. Sci. 2008, 46(5): 430–435.

  • Malenović, A., Medenica, M., Ivanović, D., Jančić, B.: Influence of structural and interfacial properties of microemulsion eluent on chromatographic separation of simvastatin and its impurities. J. Chromatogr. A 2006, 1131(1–2): 67–73.

  • Medenica M., Jančić B., Ivanović D., Malenović A.: Experimental design in RP–HPLC analysis of imatinib mesylate and its impurity. J. Chromatogr. A, 2004; 1031: 243–248.

  • Medenica, M., Ivanović D., Marković, S., Malenović A., Mišljenović, Đ.: Optimization of RP–HPLC method for Drug Control Analysis. J. Liq. Chromatogr. Related Technol. 2003; 26(20): 3401–3412.

  • Ivanović, D., Medenica, M., Nivaud–Guernet, E., Guernet, M.: Fourth–derivative spectrophotometric determination of some pharmaceutical substances. Spectrosc. Lett. 1995; 28(4): 557–571.